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Olanzapine is also used in mood disturbances of bipolar I disorder and in combination with other agents for treatment of resistant depression in adults.

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Although metabolized by multiple enzyme systems, induction or inhibition of a single enzyme may appreciably alter drug clearance.

Experts allege that both the FDA and Eli Lilly had knowledge of serious Zyprexa risks before this drug was even approved for the treatment of schizophrenia and bipolar disorder in the United States.

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